Hydroxysafflor yellow A (HSYA) targets the NF-κB and MAPK pathways and ameliorates the development of osteoarthritis
Author:
Affiliation:
1. Department of Orthopaedics
2. The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University
3. Wenzhou
4. China
5. The Second School of Medicine
Abstract
The inflammatory environment has been demonstrated to be strongly associated with the progression of osteoarthritis (OA).
Funder
National Natural Science Foundation of China
Natural Science Foundation of Zhejiang Province
Wenzhou Municipal Science and Technology Bureau
Publisher
Royal Society of Chemistry (RSC)
Subject
General Medicine,Food Science
Link
http://pubs.rsc.org/en/content/articlepdf/2018/FO/C8FO00732B
Reference52 articles.
1. Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix
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3. The Role of Inflammatory and Anti-Inflammatory Cytokines in the Pathogenesis of Osteoarthritis
4. Role of interleukin-1 and tumor necrosis factor ? in matrix degradation of human osteoarthritic cartilage
5. Nitric oxide and inflammatory mediators in the perpetuation of osteoarthritis
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