Reactivity studies of 3-alkoxy-7-amino-4-chloroisocoumarins (β-amyloid peptide inhibitors)versus different classes of amines
Author:
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2003/OB/B209733H
Reference6 articles.
1. New protease inhibitors prevent γ-secretase-mediated production of Aβ40/42 without affecting Notch cleavage
2. Secretase Targets for Alzheimer's Disease: Identification and Therapeutic Potential
3. Mechanism-Based Isocoumarin Inhibitors for Blood Coagulation Serine Proteases. Effect of the 7-Substituent in 7-Amino-4-chloro-3-(isothioureidoalkoxy)isocoumarins on Inhibitory and Anticoagulant Potency
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1. A dearomatization–rearomatization strategy for construction of 4H-quinolizin-4-ones via C–H bond functionalization of pyridines;Organic Chemistry Frontiers;2024
2. Metal-Free Synthesis of 4-Chloroisocoumarins by TMSCl-Catalyzed NCS-Induced Chlorinative Annulation of 2-Alkynylaryloate Esters;The Journal of Organic Chemistry;2019-11-19
3. Further characterization of a putative serine protease contributing to the γ-secretase cleavage of β-amyloid precursor protein;Bioorganic & Medicinal Chemistry;2013-02
4. New Synthetic Reactions Using Conjugate Addition Reactions of Active Methine Compounds to Alkynyl Imines and Ketones;Journal of Synthetic Organic Chemistry, Japan;2006
5. N-Acyl substituted 7-amino-4-chloroisocoumarin: A peptide degradation model via an imide mechanism;Bioorganic & Medicinal Chemistry Letters;2004-04
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