C(sp3)–H hydroxylation of fluorenes, oxindoles and benzofuranones with a Mg(NO3)2–HP(O)Ph2 oxidation system-Reference-Cited by-同舟云学术

C(sp3)–H hydroxylation of fluorenes, oxindoles and benzofuranones with a Mg(NO3)2–HP(O)Ph2 oxidation system

Published:2019 Issue:17 Volume:6 Page:3167-3171
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Hu Chen¹²³⁴⁵,Hong Gang⁶⁷⁸⁹¹⁰^ORCID,Nahide Pradip D.⁶⁷⁸⁹¹⁰^ORCID,He Yuchen¹²³⁴⁵,Zhou Chen¹²³⁴⁵,Kozlowski Marisa C.⁶⁷⁸⁹¹⁰,Wang Limin¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory for Advanced Materials

2. Institute of Fine Chemicals and School of Chemistry & Molecular Engineering

3. East China University of Science and Technology

4. Shanghai 200237

5. PR China

6. Department of Chemistry

7. Roy and Diana Vagelos Laboratories

8. University of Pennsylvania

9. Philadelphia

10. USA

Abstract

A novel oxidation system in which magnesium nitrate is used as an oxidant in the presence of diphenylphosphine oxide permits the C(sp³)–H hydroxylation of fluorenes, oxindoles, and benzofuranones.

Funder

National Natural Science Foundation of China

National Institutes of Health

Central Universities in China

Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

China Scholarship Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/QO/C9QO00778D

Reference65 articles.

1. Adding Aliphatic C–H Bond Oxidations to Synthesis

2. If CH Bonds Could Talk: Selective CH Bond Oxidation

3. Phase-Transfer-Catalyzed Enantioselective α-Hydroxylation of Acyclic and Cyclic Ketones with Oxygen

4. A Comparative Mechanistic Study of Cu-Catalyzed Oxidative Coupling Reactions with N-Phenyltetrahydroisoquinoline

5. Overcoming the “Oxidant Problem”: Strategies to Use O2 as the Oxidant in Organometallic C–H Oxidation Reactions Catalyzed by Pd (and Cu)

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