Cellular uptake, imaging and pathotoxicological studies of a novel Gd[iii]–DO3A-butrol nano-formulation

Author:

Mohammadi Elham1234,Amanlou Massoud5678,Sadat Ebrahimi Seyed Esmaeil5678,Hamedani Morteza Pirali5678,Mahrooz Abdolkarim9310,Mehravi Bita11128,Emami Baharak Abd13148,Aghasadeghi Mohammad Reza15148,Bitarafan-Rajabi Ahmad161718128,Pour Ali Akbar Hamid Reza1920128,Ardestani Mehdi Shafiee21678

Affiliation:

1. Department of Biochemistry

2. Faculty of Biochemistry

3. Mazandaran University of Medical Sciences

4. , Iran

5. Department of Medicinal Chemistry

6. Faculty of Pharmacy

7. Tehran University of Medical Sciences

8. Tehran, Iran

9. Molecular and Cell Biology Research Center

10. Sari, Iran

11. Faculty of Advanced Technologies in Medicine

12. Iran University of Medical Sciences

13. National Cell Bank

14. Pasteur Institute of Iran

15. Department of Hepatitis and AIDS

16. Cardiovascular Interventional Research Centre

17. Department of Nuclear Medicine

18. Rajaei Cardiovasular, Medical & Research Center

19. Cardiovasular, Medical & Research Center

20. Radiology Department

21. Department of Radiopharmacy

Abstract

The high adaptability of dendrimer-based contrast agents (CAs) is ideal for the reliable molecular imaging of cancerous tissues.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference39 articles.

1. J. Moscow and K.Cowan, Cecil Medicine, Saunders Elsevier Publications, Philadelphia, 23rd edn, 2007

2. Next Generation, High Relaxivity Gadolinium MRI Agents

3. Gd3+-DTPA-Meglumine-Anionic Linear Globular Dendrimer G1: Novel Nanosized Low Toxic Tumor Molecular MR Imaging Agent

4. Cancer is a Preventable Disease that Requires Major Lifestyle Changes

5. D. Weishaupt , V. D.Köchli and B.Marincek, Springer, 2003

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