Microfluidic organ-on-a-chip model of the outer blood–retinal barrier with clinically relevant read-outs for tissue permeability and vascular structure-Reference-Cited by-同舟云学术

Microfluidic organ-on-a-chip model of the outer blood–retinal barrier with clinically relevant read-outs for tissue permeability and vascular structure

Published:2021 Issue:2 Volume:21 Page:272-283
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Arık Yusuf B.¹²³⁴⁵^ORCID,Buijsman Wesley¹²³⁴⁵^ORCID,Loessberg-Zahl Joshua⁶²⁷³⁴^ORCID,Cuartas-Vélez Carlos⁸²³⁴⁵,Veenstra Colin⁸²³⁴⁵,Logtenberg Sander¹²³⁴⁵,Grobbink Anne M.¹²³⁴⁵,Bergveld Piet⁶²⁷³⁴,Gagliardi Giuliana⁹¹⁰¹¹¹²⁵,den Hollander Anneke I.⁹¹⁰¹¹¹²⁵^ORCID,Bosschaart Nienke⁸²³⁴⁵,van den Berg Albert⁶²⁷³⁴^ORCID,Passier Robert¹²³⁴⁵^ORCID,van der Meer Andries D.¹²³⁴⁵^ORCID

Affiliation:

1. Applied Stem Cell Technologies

2. Technical Medical Centre

3. University of Twente

4. Enschede

5. The Netherlands

6. BIOS Lab on a Chip group

7. MESA+ Institute for Nanotechnology

8. Biomedical Photonic Imaging Group

9. Department of Ophthalmology

10. Donders Institute for Brain, Cognition and Behaviour

11. Radboud University Medical Centre

12. Nijmegen

Abstract

This organ-on-a-chip device of the outer blood retinal barrier will allow future studies of complex disease mechanisms and treatments of visual disorders using clinically relevant endpoints in vitro.

Funder

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/LC/D0LC00639D

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