In vivo visualization of osteoarthritic hypertrophic lesions

Author:

Hu Hai-Yu12345,Lim Ngee-Han6789,Juretschke Hans-Paul10115,Ding-Pfennigdorff Danping10115,Florian Peter10115,Kohlmann Markus10115,Kandira Abdullah10115,Peter von Kries Jens10115,Saas Joachim10115,Rudolphi Karl A.10115,Wendt K. Ulrich10115,Nagase Hideaki10115,Plettenburg Oliver10115,Nazare Marc101151213,Schultz Carsten12345

Affiliation:

1. European Molecular Biology Laboratory (EMBL)

2. Interdisciplinary Chemistry Group

3. Cell Biology and Biophysics Unit

4. 69117 Heidelberg

5. Germany

6. Kennedy Institute of Rheumatology

7. University of Oxford

8. Headington

9. UK

10. Sanofi-Aventis Deutschland GmbH

11. 65962 Frankfurt

12. Leibniz-Institut für Molekulare Pharmakologie (FMP)

13. Campus Berlin-Buch

Abstract

Cartilage-binding bimodal MRI and fluorescent probes were developed to monitor osteoarthritic damage in animal models over extended periods of time.

Funder

CHIST-ERA

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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