Stereospecific nucleophilic substitution at tertiary and quaternary stereocentres

Author:

Lanke Veeranjaneyulu1234,Marek Ilan1234ORCID

Affiliation:

1. Schulich Faculty of Chemistry

2. Technion – Israel Institute of Technology

3. Technion City 3200009

4. Israel

Abstract

In this minireview, we summarized the fascinating and rich area of stereoselective or stereospecific nucleophilic substitution at tertiary and quaternary carbon centres.

Funder

H2020 European Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Reference56 articles.

1. Walden Inversion and Reaction Mechanism: Walden Inversion in the Acid Hydrolysis of Carboxylic Esters by Unimolecular Alkyl Fission

2. Mechanism and kinetics of substitution at a saturated carbon atom

3. Reactions of halides in solution

4. G. W. Wheland , Structure and Mechanism in Organic Chemistry , ed. C. K. Ingold and N. Y. Ithaca , Cornell Univ. Press , 1953 , p. 828

5. S. R. Hartshorn , Aliphatic Nucleophilic Substitution , Cambridge University Press , London , 1973

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