Unraveling ligand exchange reactions in linear neutral Au(<scp>i</scp>) and Cu(<scp>i</scp>) N-heterocyclic carbene complexes for biological applications-Reference-Cited by-同舟云学术

Unraveling ligand exchange reactions in linear neutral Au(i) and Cu(i) N-heterocyclic carbene complexes for biological applications

Published:2024 Issue:5 Volume:48 Page:2040-2047
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Rodrigues Gustavo C.¹^ORCID,Barrionuevo Manoel V. F.¹,San-Miguel Miguel A.¹^ORCID,Abbehausen Camilla¹^ORCID

Affiliation:

1. Institute of Chemistry, University of Campinas – UNICAMP, CEP 13083-970, P.O. Box 6154, Campinas, São Paulo, Brazil

Abstract

Linear complexes of the form [M(NHC)Cl] (M = Au(i) or Cu(i), NHC = N-heterocyclic carbene) are promising drug candidates due to their potent in vitro antitumor, antibacterial, and antiparasitic activities.

Funder

Fundação de Amparo à Pesquisa do Estado de São Paulo

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NJ/D3NJ04945K

Reference54 articles.

1. The History of Gold Therapy for Tuberculosis

2. The history of gold therapy in rheumatoid disease

3. Medicinal Applications of Gold(I/III)-Based Complexes Bearing N-Heterocyclic Carbene and Phosphine Ligands

4. A “Golden Age” for the discovery of new antileishmanial agents: Current status of leishmanicidal gold complexes and prospective targets beyond the trypanothione system

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