Friedel–Crafts alkylation with α-bromoarylacetates for the preparation of enantioenriched 2,2-diarylethanols-Reference-Cited by-同舟云学术

Friedel–Crafts alkylation with α-bromoarylacetates for the preparation of enantioenriched 2,2-diarylethanols

Published:2019 Issue:18 Volume:17 Page:4554-4563
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Kim Yongtae¹²³⁴,Choi Yun Soo¹²³⁴,Hong Su Kyung¹²³⁴,Park Yong Sun¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. Konkuk University

3. Seoul 05029

4. Republic of Korea

Abstract

Highly enantioenriched 2,2-diarylethanols can be efficiently synthesized using the AgOTf-promoted Friedel–Crafts alkylation of (hetero)arenes with configurationally labile α-bromoarylacetates.

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/OB/C9OB00706G

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