Beyond darunavir: recent development of next generation HIV-1 protease inhibitors to combat drug resistance-Reference-Cited by-同舟云学术

Beyond darunavir: recent development of next generation HIV-1 protease inhibitors to combat drug resistance

Published:2022 Issue:84 Volume:58 Page:11762-11782
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Ghosh Arun K.¹^ORCID,Weber Irene T.²,Mitsuya Hiroaki³⁴⁵

Affiliation:

1. Department of Chemistry and Department of Medicinal Chemistry, Purdue University, West Lafayette, IN 47907, USA

2. Departments of Biology and Chemistry, Molecular Basis of Disease, Georgia State University, Atlanta, GA 30303, USA

3. Departments of Hematology and Infectious Diseases, Kumamoto University School of Medicine, Kumamoto 860-8556, Japan

4. Experimental Retrovirology Section, HIV and AIDS Malignancy Branch, National Cancer Institute, Bethesda, MD 20892, USA

5. Center for Clinical Sciences, National Center for Global Health and Medicine, Shinjuku, Tokyo 162-8655, Japan

Abstract

We describe design and syntheses of a new generation of exceptionally highly potent non-peptidic HIV-1 protease inhibitors.

Funder

National Institutes of Health

U.S. Department of Energy

Basic Energy Sciences

Office of Science

Ministry of Health, Labour and Welfare

Japan Agency for Medical Research and Development

National Center for Global Health and Medicine

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CC/D2CC04541A

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