Slow-targeted release of a ruthenium anticancer agent from vitamin B12 functionalized marine diatom microalgae
Author:
Affiliation:
1. Department of Chemistry
2. Fribourg University
3. 1700 Fribourg
4. Switzerland
5. Adolphe Merkle Institute
Abstract
Bio-inspired drug capsules: The synthesis of a new vitamin-B12 modified biomaterial with increased static adherence properties toward cancer cell lines, allowed the targeted delivery of a poorly water-soluble ruthenium drug with an unprecedented release profile.
Funder
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
Publisher
Royal Society of Chemistry (RSC)
Subject
Inorganic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/DT/C8DT02914H
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