Targeted and direct intracellular delivery of native DNAzymes enables highly specific gene silencing-Reference-Cited by-同舟云学术

Targeted and direct intracellular delivery of native DNAzymes enables highly specific gene silencing

Published:2020 Issue:33 Volume:11 Page:8966-8972
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Li Xia¹²³⁴⁵,Yang Fang¹²³⁴⁵,Zhou Wenjiao¹²³⁴⁵,Yuan Ruo¹²³⁴⁵,Xiang Yun¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Luminescence Analysis and Molecular Sensing

2. Ministry of Education

3. School of Chemistry and Chemical Engineering

4. Southwest University

5. Chongqing 400715

Abstract

The stimuli-responsive and constrained aptamer/DNAzyme catenane nanostructure enables the targeted delivery of native DNAzymes for highly specific gene silencing.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC03974H

Reference45 articles.

1. Gene silencing by microRNAs: contributions of translational repression and mRNA decay

2. Accurate cancer cell identification and microRNA silencing induced therapy using tailored DNA tetrahedron nanostructures

3. DNAzyme-based therapeutics for cancer treatment

4. Regulation of Cell Proliferation and Migration by Keratin19-Induced Nuclear Import of Early Growth Response-1 in Breast Cancer Cells

5. DNA enzymes as potential therapeutics: towards clinical application of 10-23 DNAzymes

Cited by 19 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Ingenious dual-circle DNA walker-mediated electrochemical biosensor for rapid and ultrasensitive detection of microRNA;Biosensors and Bioelectronics;2025-01

2. Nanosized DNA Hydrogel Functionalized with a DNAzyme Tetrahedron for Highly Efficient Gene Silencing;Biomacromolecules;2024-07-04

3. Construction of Smart DNA‐Based Drug Delivery Systems for Cancer Therapy;Small;2024-02-20

4. Functional Study of Conjugate of VASN Aptamer-DNAzyme for Telomerase Reverse Transcriptase;PROG BIOCHEM BIOPHYS;2023

5. Therapeutic DNAzymes: From Structure Design to Clinical Applications;Advanced Materials;2023-06-07