Exploitation of nanoparticle–protein corona for emerging therapeutic and diagnostic applications

Author:

Palchetti S.12345ORCID,Pozzi D.12345,Mahmoudi M.678910,Caracciolo G.12345

Affiliation:

1. Department of Molecular Medicine

2. Rome

3. Italy

4. Istituti Fisioterapici Ospitalieri

5. Istituto Regina Elena

6. Department of Nanotechnology and Nanotechnology Research Center

7. Faculty of Pharmacy

8. Tehran University of Medical Sciences

9. Tehran 13169-43551

10. Iran

Abstract

Exposure of nanoparticles (NPs) to biological fluids (e.g., plasma, interstitial fluid, and cytoplasm) leads to the absorption of proteins on the NP surface, forming a protein corona (PC) that drastically influences the NP physicochemical properties.

Funder

Ministero della Salute

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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