Design, synthesis and DNA interactions of a chimera between a platinum complex and an IHF mimicking peptide
Author:
Affiliation:
1. Institut für Organische und Biomolekulare Chemie
2. Georg-August-Universität Göttingen
3. 37077 Göttingen
4. Germany
5. Biokemi
6. Kemicentrum
7. Lund Universitet
8. Lund
9. Sweden
Abstract
A platinum complex/peptide chimera shows specific DNA binding and covalent platination with potential as a novel chemotherapeutic.
Funder
Deutsche Forschungsgemeinschaft
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB01885D
Reference53 articles.
1. X-Ray Structure of the Major Adduct of the Anticancer Drug Cisplatin with DNA: cis -[Pt(NH 3 ) 2 {d(pGpG)}]
2. Reevaluation of interaction of cis-dichloro(ethylenediamine)platinum(II) with DNA
3. The mechanism of action of platinum antitumor drugs
4. Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin
5. The resurgence of platinum-based cancer chemotherapy
Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Nano-bio interaction: An overview on the biochemical binding of DNA to inorganic nanoparticles for the development of anticancer and antibacterial nano-platforms;International Journal of Biological Macromolecules;2023-01
2. Preparation, cytotoxic activity and DNA interaction studies of new platinum(II) complexes with 1,10-phenanthroline and 5-alkyl-1,3,4-oxadiazol-2(3H)-thione derivatives;Journal of Inorganic Biochemistry;2022-12
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3