Binding mechanism of nine N-phenylpiperazine derivatives and α1A-adrenoceptor using site-directed molecular docking and high performance affinity chromatography-Reference-Cited by-同舟云学术

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Binding mechanism of nine N-phenylpiperazine derivatives and α1A-adrenoceptor using site-directed molecular docking and high performance affinity chromatography

Published:2015 Issue:70 Volume:5 Page:57050-57057
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Zhao X. F.¹²³⁴⁵,Wang J.¹²³⁴⁵,Liu G. X.¹²³⁴⁵,Fan T. P.¹²³⁴⁵,Zhang Y. J.¹²³⁴⁵,Yu J.¹²³⁴⁵,Wang S. X.¹²³⁴⁵,Li Z. J.⁶⁷⁸²⁹,Zhang Y. Y.⁶⁷⁸²⁹,Zheng X. H.¹²³⁴⁵

Affiliation:

1. Key Laboratory of Resource Biology and Biotechnology in Western China

2. Ministry of Education

3. College of Life Sciences

4. Northwest University

5. Xi’an 710069

6. Institute of Vascular Medicine

7. Peking University

8. Third Hospital and Key Laboratory of Molecular Cardiovascular Sciences

9. Beijing 100083

Abstract

Investigating the binding mechanism of α_1A-adrenoceptor and its specific ligands by affinity chromatography.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA10812H

Reference45 articles.

1. Silodosin: A selective α1A-adrenergic receptor antagonist for the treatment of benign prostatic hyperplasia

2. Alpha-1-adrenergic receptors: Targets for agonist drugs to treat heart failure

3. Structure-based discovery of 2-adrenergic receptor ligands

4. α1-Adrenergic receptor subtypes in the central nervous system: insights from genetically engineered mouse models

5. Identification of Critical Determinants of α1-Adrenergic Receptor Subtype Selective Agonist Binding

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Affinity Chromatographic Method for Determining Drug–Protein Interaction with Enhanced Speed Than Typical Frontal Analysis;Langmuir;2023-07-16

2. Site-selective covalently immobilized alpha 1A adrenergic receptor for thermodynamic and extra-thermodynamic study of four ligands binding to the receptor by chromatographic methods;Journal of Chromatography A;2022-02

3. Development and characterization of a selective chromatographic approach to the rapid discovery of ligands binding to muscarinic-3 acetylcholine receptor;Journal of Chromatography A;2021-09

4. Potentiometric Signal Transduction for Selective Determination of 1-(3-Chlorophenyl)piperazine “Legal Ecstasy” Through Biomimetic Interaction Mechanism;Chemosensors;2019-09-16

5. Crystal structures, absolute configurations and molecular docking studies of naftopidil enantiomers as α 1D -adrenoceptor antagonists;Acta Pharmaceutica Sinica B;2017-07

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