Cobaltoceniumethynyl gold(i) as an unusual heterodinuclear bioorganometallic fragment to study the biological properties of alkynyl gold complexes-Reference-Cited by-同舟云学术

Cobaltoceniumethynyl gold(i) as an unusual heterodinuclear bioorganometallic fragment to study the biological properties of alkynyl gold complexes

Published:2016 Issue:4 Volume:45 Page:1345-1348
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Vanicek S.¹²³⁴⁵,Kopacka H.¹²³⁴⁵,Wurst K.¹²³⁴⁵,Vergeiner S.⁶³⁴⁵⁷,Kankowski S.⁸⁹¹⁰¹¹,Schur J.⁸⁹¹⁰¹¹,Bildstein B.¹²³⁴⁵,Ott I.⁸⁹¹⁰¹¹

Affiliation:

1. Institute of General

2. Inorganic and Theoretical Chemistry

3. University of Innsbruck

4. Center for Chemistry and Biomedicine

5. A-6020 Innsbruck

6. Institute of Organic Chemistry

7. Austria

8. Institute of Medicinal and Pharmaceutical Chemistry

9. Technische Universität Braunschweig

10. 38106 Braunschweig

11. Germany

Abstract

A cobaltoceniumethynyl gold(i) complex with a triphenylphosphane ligand triggered efficient cytotoxic effects in cancer cells in contrast to a derivative with two cobaltocenium moieties.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/DT/C5DT04796J

Reference23 articles.

1. On the medicinal chemistry of gold complexes as anticancer drugs

2. A golden future in medicinal inorganic chemistry: the promise of anticancer gold organometallic compounds

3. Chemical biology of anticancer gold(iii) and gold(i) complexes

4. On the Biological Properties of Alkynyl Phosphine Gold(I) Complexes

5. Luminescent alkynyl-gold(i) coumarin derivatives and their biological activity

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