Curcumin derivatives as photosensitizers in photodynamic therapy: photophysical properties and in vitro studies with prostate cancer cells

Author:

Kazantzis K. T.12345,Koutsonikoli K.12345,Mavroidi B.67895ORCID,Zachariadis M.1011121314,Alexiou P.67895,Pelecanou M.67895ORCID,Politopoulos K.12345,Alexandratou E.12345ORCID,Sagnou M.67895

Affiliation:

1. Laboratory of Biomedical Optics and Applied Biophysics

2. School of Electrical and Computer Engineering

3. National Technical University of Athens

4. 15780 Athens

5. Greece

6. Laboratories of Structural Studies of Biomolecules and Pharmaceuticals with NMR

7. Institute of Biosciences and Applications

8. NCSR “Demokritos”

9. Athens

10. Bioimaging and Cell analysis

11. Material and Chemical Characterisation Facility

12. University of Bath

13. Bath BA2 7AY

14. UK

Abstract

Increased absorption maximum for the dimethylaminocurcumin with strong PD effect on prostate cancer cells; Intense PD effect of curcumin III on prostate cancer cells; Exciting biphasic PD response by curcumin I and cinnamaldehyde-derived curcumin.

Funder

European Regional Development Fund

Stavros Niarchos Foundation

Publisher

Springer Science and Business Media LLC

Subject

Physical and Theoretical Chemistry

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