Catalytic C–H alkynylation of benzylamines and aldehydes with aldimine-directing groups generated <i>in situ</i>-Reference-Cited by-同舟云学术

Catalytic C–H alkynylation of benzylamines and aldehydes with aldimine-directing groups generated in situ

Published:2023 Issue:42 Volume:59 Page:6355-6358
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Zhou Jiao¹,Jiao Tenggang¹,Fu Qiang¹^ORCID,Wang Jun¹,Lu Ji¹^ORCID,Yang Lin¹^ORCID,Wei Jun¹,Wei Siping¹^ORCID,Cong Xuefeng²^ORCID,Hao Na¹

Affiliation:

1. Green Pharmaceutical Technology Key Laboratory of Luzhou, Central Nervous System Drug Key Laboratory of Sichuan Province, Department of Medicinal Chemistry, School of Pharmacy, Southwest Medical University, Luzhou 646000, China

2. Institute of Molecular Plus, Tianjin University, 92 Weijin Road, Tianjin, 300072, China

Abstract

Iridium-catalysed regioselective C–H alkynylation of unprotected primary benzylamines and aliphatic aldehydes has been developed using in situ-installed aldimine directing groups.

Funder

National Natural Science Foundation of China

Southwest Medical University

Huaiyin Institute of Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC01414B

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