Synthesis of 2-trifluoromethyl benzimidazoles, benzoxazoles, and benzothiazoles <i>via</i> condensation of diamines or amino(thio)phenols with CF<sub>3</sub>CN-Reference-Cited by-同舟云学术

Synthesis of 2-trifluoromethyl benzimidazoles, benzoxazoles, and benzothiazoles via condensation of diamines or amino(thio)phenols with CF₃CN

Published:2023 Issue:23 Volume:21 Page:4788-4793
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Lin Bo¹,Yao Yunfei¹,Wu Minze²,Qin Lu²,Chen Shouxiong²,You Yi¹,Weng Zhiqiang¹²^ORCID

Affiliation:

1. Key Laboratory of Molecule Synthesis and Function Discovery, College of Chemistry, Fuzhou University, Fuzhou, 350108, China

2. Fujian Provincial University Engineering Research Center of Green Materials and Chemical Engineering, and Fujian Engineering Research Center of New Chinese Lacquer Material, College of Materials and Chemical Engineering, Minjiang University Fuzhou, 350108, China

Abstract

A new method for the synthesis of 2-trifluoromethyl benzimidazoles, benzoxazoles, and benzothiazoles via the condensation of diamines or amino(thio)phenols with in situ generated CF3CN is developed.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Fujian Province

Minjiang University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB00517H

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1. Imidazole and Benzimidazole Derivatives as Chemotherapeutic Agents