A dual organelle-targeting photosensitizer based on curcumin for enhanced photodynamic therapy-Reference-Cited by-同舟云学术

A dual organelle-targeting photosensitizer based on curcumin for enhanced photodynamic therapy

Published:2023 Issue:45 Volume:11 Page:10836-10844
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Wang Yanping¹²,Li Xuewei¹²,Liu Weimin¹²³^ORCID,Sha Jie¹²,Yu Zhe¹²,Wang Shuai¹²,Ren Haohui¹³,Zhang Wenjun⁴^ORCID,Lee Chun-Sing⁴^ORCID,Wang Pengfei¹²^ORCID

Affiliation:

1. Key Laboratory of Photochemical Conversion and Optoelectronic Materials & CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China

2. School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China

3. Qingdao Casfuture Research Institute CO., LTD, P. R. China

4. Department of Materials Science and Engineering & Center of Super-Diamond and Advanced Films, City University of Hong Kong, Hong Kong, P. R. China

Abstract

A curcumin-based photosensitizer, CN, can specifically target lipid droplets (LDs) and the endoplasmic reticulum (ER) simultaneously, which can enhance PDT effect of CN due to apoptosis by destroying the ER and ferroptosis by oxidizing PUFAs in LDs.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2023/TB/D3TB01648J

Reference41 articles.

1. Photosensitizers for Photodynamic Therapy

2. Photodynamic therapy and anti-tumour immunity