Improved synthesis of DA364, an NIR fluorescence RGD probe targeting α<sub>v</sub>β<sub>3</sub> integrin-Reference-Cited by-同舟云学术

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Improved synthesis of DA364, an NIR fluorescence RGD probe targeting α_vβ₃ integrin

Published:2023 Issue:42 Volume:21 Page:8584-8592
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Maschio Rachele¹^ORCID,Buonsanti Federica²,Crivellin Federico²,Ferretti Fulvio²,Lattuada Luciano²^ORCID,Maisano Federico²^ORCID,Orio Laura²^ORCID,Pizzuto Lorena²,Campanella Raphael³,Clouet Anthony³,Cavallotti Camilla⁴^ORCID,Giovenzana Giovanni B.¹⁴^ORCID

Affiliation:

1. Dipartimento di Scienze del Farmaco, Università del Piemonte Orientale, Largo Donegani 2/3, 28100 Novara, Italy

2. Bracco Imaging Spa, Bracco Research Centre, Via Ribes 5, 10010 Colleretto Giacosa, TO, Italy

3. Bracco Suisse SA, Route de la Galaise 31, 1228 Plan le Ouates, Switzerland

4. CAGE Chemicals Srl, Via Bovio 6, 28100 Novara, Italy

Abstract

Significant improvements in the synthetic approach to the αvβ3-targeted NIR-fluorescent probe DA364 are reported.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB01206A

Reference60 articles.

1. Imaging in the era of molecular oncology

2. A Molecular Imaging Primer: Modalities, Imaging Agents, and Applications

3. Optical Imaging Modalities: Principles and Applications in Preclinical Research and Clinical Settings

4. In vivo near-infrared fluorescence imaging

5. Light in diagnosis, therapy and surgery

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