Bifunctional folic-conjugated aspartic-modified Fe<sub>3</sub>O<sub>4</sub> nanocarriers for efficient targeted anticancer drug delivery-Reference-Cited by-同舟云学术

Bifunctional folic-conjugated aspartic-modified Fe₃O₄ nanocarriers for efficient targeted anticancer drug delivery

Published:2022 Issue:8 Volume:12 Page:4961-4971
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Khalil Munawar¹^ORCID,Haq Ely Arina¹,Dwiranti Astari²,Prasedya Eka Sunarwidhi³⁴,Kitamoto Yoshitaka⁵

Affiliation:

1. Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, 16424 Depok, West Java, Indonesia

2. Department of Biology, Cellular and Molecular Mechanism in Biological System (CEMBIOS) Research Group, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, 16424 Depok, West Java, Indonesia

3. Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Mataram, 83125 Lombok, West Nusa Tenggara, Indonesia

4. Bioscience and Biotechnology Research Center, Faculty of Mathematics and Natural Sciences, University of Mataram, 83125 Lombok, West Nusa Tenggara, Indonesia

5. Department of Materials Science and Engineering, School of Materials and Chemical Technology, Tokyo Institute of Technology, Yokohama 226-8503, Japan

Abstract

Aspartic acid was used as an anchoring molecule for the conjugation of folic acid and doxorubicin to Fe3O4 nanoparticles. The as-prepared bifunctional folic-conjugated aspartic-modified Fe3O4 nanocarrier was shown to be as an efficient targeted anticancer drug delivery.

Funder

Ministry of Research and Technology/National Research and Innovation Agency

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D1RA08776B

Reference58 articles.

1. Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects

2. Chitosan overlaid Fe3O4/rGO nanocomposite for targeted drug delivery, imaging, and biomedical applications

3. Nanoparticles-based drug delivery and gene therapy for breast cancer: Recent advancements and future challenges