Iron-catalyzed alkoxyl radical-mediated C–C bond cleavage/phosphorothiolation: a new approach to functionalized <i>S</i>-alkyl phosphorothioates-Reference-Cited by-同舟云学术

Iron-catalyzed alkoxyl radical-mediated C–C bond cleavage/phosphorothiolation: a new approach to functionalized S-alkyl phosphorothioates

Published:2023 Issue:28 Volume:21 Page:5855-5860
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Bai Ming¹,Liu Shuai¹,Xin Hong¹,Yang Xu²,Duan Xin-Hua¹²^ORCID,Guo Li-Na¹^ORCID

Affiliation:

1. Department of Chemistry, School of Chemistry, Xi'an Key Laboratory of Sustainable Energy Material Chemistry and Engineering Research Center of Energy Storage Materials and Devices, Ministry of Education, Xi'an Jiaotong University, Xi'an 710049, P. R. China

2. School of Electrical Engineering, Xi'an Jiaotong University, Xi'an, 710049, P. R. China

Abstract

A cheap iron-catalyzed alkoxyl radical-mediated C–C bond cleavage/phosphorothiolation cascade is presented. This protocol features mild and redox neutral conditions, wide substrate scope and easy scalability.

Funder

National Natural Science Foundation of China

Natural Science Basic Research Program of Shaanxi Province

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB00673E

Reference47 articles.

1. Synthesis of novel phosphorothioates and phosphorodithioates and their differential inhibition of cholinesterases

2. 5′-Phosphate and 5′-Phosphonate Ester Derivatives of (N)-Methanocarba Adenosine with in Vivo Cardioprotective Activity

3. Cyclic diguanylate analogues: Facile synthesis, STING binding mode and anti-tumor immunity delivered by cytidinyl/cationic lipid

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