Substituent effects on stereoselectivity of dihalocarbene reactions with cyclohexadiene and on the reactivity of bis-dihalocyclopropanes in electrophilic nitrations en route to pyrimidine N-oxides-Reference-Cited by-同舟云学术

Substituent effects on stereoselectivity of dihalocarbene reactions with cyclohexadiene and on the reactivity of bis-dihalocyclopropanes in electrophilic nitrations en route to pyrimidine N-oxides

Published:2017 Issue:44 Volume:15 Page:9433-9441
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Sedenkova Kseniya N.¹²³⁴⁵,Averina Elena B.¹²³⁴⁵^ORCID,Grishin Yuri K.¹²³⁴,Kolodyazhnaya Julia V.¹²³⁴,Rybakov Victor B.¹²³⁴,Kuznetsova Tamara S.¹²³⁴,Hughes Audrey⁶⁷⁸⁹,Gomes Gabriel dos Passos⁶⁷⁸⁹^ORCID,Alabugin Igor V.⁶⁷⁸⁹^ORCID,Zefirov Nikolay S.¹²³⁴⁵

Affiliation:

1. Lomonosov Moscow State University

2. Department of Chemistry

3. Moscow 119991

4. Russia

5. IPhAc RAS

6. Department of Chemistry & Biochemistry

7. Florida State University

8. Tallahassee

9. USA

Abstract

Bis-adducts of cyclohexa-1,4-diene with dihalocarbenes were synthesized and investigated in heterocyclization.

Funder

Division of Chemistry

Russian Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB02463K

Reference54 articles.

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2. Significance and Biological Importance of Pyrimidine in the Microbial World

3. Pyrimidine-based antimalarials: design strategies and antiplasmodial effects

4. Design, synthesis, and biological evaluation of novel quinazolinyl-diaryl urea derivatives as potential anticancer agents

5. 2,4-Diaminopyrimidines as dual ligands at the histamine H 1 and H 4 receptor—H 1 /H 4 -receptor selectivity

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