An efficient and scalable synthesis of potent TLR2 agonistic PAM2CSK4-Reference-Cited by-同舟云学术

An efficient and scalable synthesis of potent TLR2 agonistic PAM2CSK4

Published:2018 Issue:18 Volume:8 Page:9587-9596
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Kaur Arshpreet¹²³⁴,Poonam Poonam¹²³⁴,Patil Madhuri T.⁵⁶⁷⁴,Mehta Surinder K.¹²³⁴^ORCID,Salunke Deepak B.¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry and Centre of Advanced Studies in Chemistry

2. Panjab University

3. Chandigarh 160014

4. India

5. Department of Chemistry

6. Mehr Chand Mahajan DAV College for Women

7. Chandigarh 160036

Abstract

Diacylated PAM₂CSK₄, a highly expensive lipopeptide with desirable aqueous solubility and a broad spectrum of cytokine/chemokine induction is a most potent dual (human and murine) Toll-Like Receptor-2 (TLR2) agonist.

Funder

Department of Biotechnology , Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA01387J

Reference42 articles.

1. Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

2. Toll-Like Receptor Signaling Pathways

3. TOLL-like receptors linking innate and adaptive immune response

4. Vaccines versus immunotherapy: Overview of approaches in deciding between options

5. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

Cited by 10 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Toll‐Like Receptor‐Based Adjuvants: A Gateway Toward Improved Malaria Vaccination;Drug Development for Malaria;2022-08-05

2. TLR2 agonistic lipopeptide enriched PLGA nanoparticles as combinatorial drug delivery vehicle;Colloids and Surfaces A: Physicochemical and Engineering Aspects;2022-08

3. Combined delivery of TLR2 and TLR7 agonists by Nanostructured lipid carriers induces potent vaccine adjuvant activity in mice;International Journal of Pharmaceutics;2022-02

4. Stereoisomeric Pam₂CS based TLR2 agonists: synthesis, structural modelling and activity as vaccine adjuvants;RSC Medicinal Chemistry;2022

5. The Potential of Calcium Phosphate Nanoparticles as Adjuvants and Vaccine Delivery Vehicles;Frontiers in Materials;2021-12-22