Design, synthesis and evaluation of 1-(1,5-bis(4-substituted phenyl)-2-methyl-1<i>H</i>-pyrrol-3-yl)-<i>N</i>-methylmethanamines as SERT inhibitors with potential antidepressant action-Reference-Cited by-同舟云学术

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Design, synthesis and evaluation of 1-(1,5-bis(4-substituted phenyl)-2-methyl-1H-pyrrol-3-yl)-N-methylmethanamines as SERT inhibitors with potential antidepressant action

Published:2023 Issue:2 Volume:14 Page:393-402
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Wunnava Anjani Uma Rani¹^ORCID,Kurati Sony Priya¹^ORCID,Eswar Kumar Kilari²,Muthyala Murali Krishna Kumar¹

Affiliation:

1. Pharmaceutical Chemistry Research Lab, Andhra University College of Pharmaceutical Science, Andhra University, Visakhapatnam, India

2. Pharmacology Department, Andhra University College of Pharmaceutical Science, Andhra University, Visakhapatnam, India

Abstract

Identification of SERT inhibition and antidepressant activity in diarylpyrrolemethylamines.

Funder

Science for Equity, Empowerment and Development Division

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/MD/D2MD00243D

Reference56 articles.

1. https://www.who.int/news-room/fact-sheets/detail/depression

2. https://www.the-scientist.com/bio-business/antidepressant-approvals-could-herald-new-era-in-psychiatric-drugs-66475

3. Improved BM212 MmpL3 Inhibitor Analogue Shows Efficacy in Acute Murine Model of Tuberculosis Infection

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