Total synthesis of (−)-8-epi-chromazonarol enabled by a unique N2H4·H2O promoted intramolecular oxa-Michael cyclization reaction-Reference-Cited by-同舟云学术

Total synthesis of (−)-8-epi-chromazonarol enabled by a unique N2H4·H2O promoted intramolecular oxa-Michael cyclization reaction

Published:2018 Issue:20 Volume:5 Page:3013-3017
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Liu Lin¹²³⁴⁵,Song Huayue¹²³⁴⁵,Chen Peng¹²³⁴⁵,Yuan Ziyun¹²³⁴⁵,Feng Shangbiao¹²³⁴⁵,Zhang Weiwei¹²³⁴⁵,Fang Bowen⁶⁷⁴⁸,Xie Xingang¹²³⁴⁵^ORCID,She Xuegong¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Applied Organic Chemistry

2. College of Chemistry and Chemical Engineering

3. Lanzhou University

4. Lanzhou

5. P. R. China

6. Chemical Engineering Institute

7. Northwest University for Nationalities

8. People's Republic of China

Abstract

The first enantioselective synthesis of 8-epi-chromazonarol was achieved by a N₂H₄·H₂O promoted highly diastereoselective oxa-Michael cyclization reaction.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/QO/C8QO00901E

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3. Some metabolites of the marine sponges Smenospongia aurea and Smenospongia (.ident.Polyfibrospongia) echina