Gene-specific regulation of hepatic selenoprotein expression by interleukin-6-Reference-Cited by-同舟云学术

Gene-specific regulation of hepatic selenoprotein expression by interleukin-6

Published:2015 Issue:11 Volume:7 Page:1515-1521
ISSN:1756-5901
Container-title:Metallomics
language:en
Short-container-title:Metallomics

Author:

Martitz J.¹²³⁴,Becker N.-P.¹²³⁴,Renko K.¹²³⁴,Stoedter M.¹²³⁴,Hybsier S.¹²³⁴,Schomburg L.¹²³⁴

Affiliation:

1. Institut für Experimentelle Endokrinologie

2. Charité – Universitätsmedizin Berlin

3. CVK

4. D-13353 Berlin, Germany

Abstract

The pro-inflammatory cytokine affects selenoprotein biosynthesis in hepatocytes directly, in favour of protective GPX2 and at the expense of Se transporter SePP and thyroid hormone deiodinase DIO1.

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2015/MT/C5MT00211G

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