NMR, CD and UV spectroscopic studies reveal uncommon binding modes of dapoxetine to native cyclodextrins-Reference-Cited by-同舟云学术

NMR, CD and UV spectroscopic studies reveal uncommon binding modes of dapoxetine to native cyclodextrins

Published:2016 Issue:104 Volume:6 Page:102315-102328
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Darcsi András¹²³⁴,Szakács Zoltán⁵⁶³⁴,Zsila Ferenc⁷⁸⁹¹⁰³,Tóth Gergő¹¹²¹²⁴,Rácz Ákos¹¹²¹²⁴,Béni Szabolcs¹²³⁴^ORCID

Affiliation:

1. Department of Pharmacognosy

2. Semmelweis University

3. Budapest

4. Hungary

5. Spectroscopic Research Department

6. Chemical Works of Gedeon Richter Plc.

7. Biomolecular Self-Assembly Group

8. Institute of Materials and Environmental Chemistry

9. Research Centre for Natural Sciences

10. Hungarian Academy of Sciences

11. Department of Pharmaceutical Chemistry

12. Budapest H-1092

Abstract

Complex formation between the selective serotonin reuptake inhibitor drug (S)-dapoxetine (Dpx) and β-, γ-, and methylated γ-cyclodextrins (CyDs) was studied by complementary experimental techniques.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA22431H

Reference51 articles.

1. Dapoxetine for Premature Ejaculation

2. Pharmaceutical Applications of Cyclodextrins. 1. Drug Solubilization and Stabilization

3. Design and Evaluation of Cyclodextrin-Based Drug Formulation

4. Introduction and General Overview of Cyclodextrin Chemistry

5. The Stability of Cyclodextrin Complexes in Solution

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