Horeau amplification in the sequential acylative kinetic resolution of (±)-1,2-diols and (±)-1,3-diols in flow-Reference-Cited by-同舟云学术

Horeau amplification in the sequential acylative kinetic resolution of (±)-1,2-diols and (±)-1,3-diols in flow

Published:2021 Issue:16 Volume:19 Page:3620-3627
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Brandolese Arianna¹²³⁴⁵,Greenhalgh Mark D.¹²³⁴⁵,Desrues Titouan⁶⁷⁸⁹¹⁰,Liu Xueyang⁶⁷⁸⁹¹⁰,Qu Shen¹²³⁴⁵,Bressy Cyril⁶⁷⁸⁹¹⁰^ORCID,Smith Andrew D.¹²³⁴⁵^ORCID

Affiliation:

1. EaStCHEM

2. School of Chemistry

3. University of St Andrews

4. St Andrews

5. UK

6. Aix Marseille Univ

7. CNRS

8. Centrale Marseille

9. iSm2 Marseille

10. France

Abstract

The sequential kinetic resolution of (±)-1,2-syn and (±)-1,3-anti-diols in flow, using the polystyrene supported isothiourea, HyperBTM, gives highly enantioenriched products using the principles of Horeau amplification.

Funder

Università degli Studi di Ferrara

University of St Andrews

Aix-Marseille Université

Centre National de la Recherche Scientifique

Agence Nationale de la Recherche

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB00304F