In vivo MRI tracking and therapeutic efficacy of transplanted mesenchymal stem cells labeled with ferrimagnetic vortex iron oxide nanorings for liver fibrosis repair

Author:

Wang Yujie12,Yu Chenggong2,Li Yuxuan2,Bao Hongying2,Li Xiaodi2,Fan Haiming3ORCID,Huang Jie2ORCID,Zhang Zhijun2ORCID

Affiliation:

1. College of Science, Shanghai University, 99 Shangda Road, Shanghai, 200444, China

2. CAS Key Laboratory of Nano-Bio Interface, Division of Nanobiomedicine, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, China

3. College of Chemistry and Materials Science, Northwest University, 1 Xue Fu Avenue, Xi'an, 710127, China

Abstract

The development and application of PEGylated ferrimagnetic vortex iron oxide nanoring (FVIO@PEG) nanotracers for long-term MRI tracking of transplanted hMSCs in the treatment of liver fibrosis are reported.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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