Dual-targeted and MRI-guided photothermal therapy via iron-based nanoparticles-incorporated neutrophils

Author:

Wang Jing12345,Mei Tianxiao12345,Liu Yang12345,Zhang Yifan12345,Zhang Ziliang12345,Hu Yihui12345,Wang Yibin62789,Wu Minliang101112139,Yang Chuanxue12345,Zhong Xiangdong12345,Chen Bingdi12345ORCID,Cui Zheng14151617,Le Wenjun12345ORCID,Liu Zhongmin12345ORCID

Affiliation:

1. Institute for Regenerative Medicine

2. Shanghai East Hospital

3. The Institute for Biomedical Engineering & Nano Science

4. School of Medicine & School of Life Sciences and Technology

5. Tongji University

6. Department of Radiology

7. Tongji University School of Medicine

8. Shanghai 200092

9. China

10. Department of Plastic Surgery

11. Changhai Hospital

12. Second Military Medical University

13. Shanghai 200433

14. Departments of Pathology

15. Wake Forest University School of Medicine

16. Winston-Salem

17. USA

Abstract

Here, we designed composites of neutrophils and NIR-sensitive nanoparticles (NSNP@Ne) to eradicate pancreatic tumors and inhibit tumor recurrence.

Funder

Natural Science Foundation of Jiangxi Province

Fundamental Research Funds for the Central Universities

Natural Science Foundation of Jiangsu Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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