Synthesis and preliminary evaluation of novel alkyl diamine linked bivalent β-carbolines as angiogenesis inhibitors-Reference-Cited by-同舟云学术

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Synthesis and preliminary evaluation of novel alkyl diamine linked bivalent β-carbolines as angiogenesis inhibitors

Published:2016 Issue:11 Volume:7 Page:2177-2183
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Guo Liang¹²³⁴⁵,Chen Wei⁵⁶⁴,Fan Wenxi⁵⁶⁴,Ma Qin⁵⁶⁴,Sun Rongqin⁷⁸⁹⁴,Shao Guang⁷⁸⁹⁴,Cao Rihui⁷⁸⁹⁴

Affiliation:

1. School of Chemistry and Chemical Engineering

2. Shihezi University

3. Shihezi 832003

4. PR China

5. Xinjiang Huashidan Pharmaceutical Co. Ltd.

6. Urumqi 830011

7. School of Chemistry

8. Sun Yat-sen University

9. Guangzhou 510275

Abstract

A series of novel bivalent β-carbolines were synthesized and evaluated as potent angiogenesis inhibitors.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MD/C6MD00360E

Reference35 articles.

1. Angiogenesis in health and disease

2. Angiogenesis as a therapeutic target

3. Inhibitors of Angiogenesis

4. β-Carboline Alkaloids: Biochemical and Pharmacological Functions

5. Antitumor agents 201.1 Cytotoxicity of harmine and β-carboline analogs

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3. Design, Synthesis, and Antitumor Activity of β-Carboline-Benzimidazole Hybrids;Chinese Journal of Organic Chemistry;2022

4. A comprehensive overview of β-carbolines and its derivatives as anticancer agents;European Journal of Medicinal Chemistry;2021-11

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