Enabling the next steps in cancer immunotherapy: from antibody-based bispecifics to multispecifics, with an evolving role for bioconjugation chemistry-Reference-Cited by-同舟云学术

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Enabling the next steps in cancer immunotherapy: from antibody-based bispecifics to multispecifics, with an evolving role for bioconjugation chemistry

Published:2022 Issue:2 Volume:3 Page:140-169
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

Thoreau Fabien¹,Chudasama Vijay¹^ORCID

Affiliation:

1. Department of Chemistry, University College London, 20 Gordon Street, London WC1H 0AJ, UK

Abstract

Immune targets and antibodies for cancer immunotherapy are reviewed. Multispecific antibody formats and bioconjugation chemistry to generate them are discussed.

Funder

European Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Molecular Biology,Biochemistry,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CB/D1CB00082A

Reference243 articles.

1. History of passive antibody administration for prevention and treatment of infectious diseases

2. Next generation antibody drugs: pursuit of the 'high-hanging fruit'

3. Continuous cultures of fused cells secreting antibody of predefined specificity

4. Therapeutic antibodies: successes, limitations and hopes for the future

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4. Chemical generation of checkpoint inhibitory T cell engagers for the treatment of cancer;Nature Chemistry;2023-07-24

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