CF3: an overlooked chromophore in VCD spectra. A review of recent applications in structural determination

Author:

Abbate Sergio1234ORCID,Longhi Giovanna1234,Mazzeo Giuseppe1234,Villani Claudio5674ORCID,Petković Silvija89104,Ruzziconi Renzo89104ORCID

Affiliation:

1. DMMT (Dipartimento di Medicina Molecolare e Traslazionale)

2. Università di Brescia

3. 25123 Brescia

4. Italy

5. Dipartimento di Chimica e Tecnologie del Farmaco

6. Università di Roma “La Sapienza”

7. 00185 Roma

8. Dipartimento di Chimica, Biologia e Biotecnologie

9. Università di Perugia

10. 06123 Perugia

Abstract

VCD allows one to investigate the configuration of stereogenic centers bearing a CF3-group and to define its interactions with nearby chemical groups.

Funder

Università degli Studi di Brescia

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference66 articles.

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2. V.Prakash Reddy , Organofluorine Compounds in Biology and Medicine , Elsevier , 2015

3. Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

4. T.Yamazaki , T.Taguchi and I.Ojima , Unique Properties of Fluorine and their Relevance to Medicinal Chemistry and Chemical Biology , in Fluorine in Medicinal Chemistry and Chemical Biology , ed. I. Ojima , Wiley , 2009

5. Fluorine and Health , ed. Tressaud and G. Haufe , Elsevier , 2008

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