Synthesis and thermal stabilities of oligonucleotides containing 2′-O,4′-C-methylene bridged nucleic acid with a phenoxazine base-Reference-Cited by-同舟云学术

Synthesis and thermal stabilities of oligonucleotides containing 2′-O,4′-C-methylene bridged nucleic acid with a phenoxazine base

Published:2017 Issue:38 Volume:15 Page:8145-8152
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Kishimoto Yuki¹²³⁴⁵^ORCID,Fujii Akane¹²³⁴⁵^ORCID,Nakagawa Osamu¹²³⁴⁵^ORCID,Nagata Tetsuya⁵⁶⁷⁴⁸^ORCID,Yokota Takanori⁵⁶⁷⁴⁸^ORCID,Hari Yoshiyuki⁹¹⁰¹¹⁴^ORCID,Obika Satoshi¹²³⁴⁵^ORCID

Affiliation:

1. Graduate School of Pharmaceutical Sciences

2. Osaka University

3. Suita

4. Japan

5. Core Research for Evolutional Science and Technology (CREST)

6. Japan Sciences and Technology Agency (JST)

7. Tokyo 102-0076

8. Department of Neurology and Neurological Science

9. Faculty of Pharmaceutical Sciences

10. Tokushima Bunri University

11. Tokushima 770-8514

Abstract

BNAP-modified ODNs showed higher binding affinities toward complementary DNA and RNA as compared to ODNs bearing 2′,4′-BNA/LNA with 5-methylcytosine or 2′-deoxyribonucleoside with phenoxazine.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB01874F

Reference47 articles.

1. Biological applications of xeno nucleic acids

2. Synthesis of 2′-O,4′-C-methyleneuridine and -cytidine. Novel bicyclic nucleosides having a fixed C3, -endo sugar puckering

3. Stability and structural features of the duplexes containing nucleoside analogues with a fixed N-type conformation, 2′-O,4′-C-methyleneribonucleosides

4. LNA (locked nucleic acids): synthesis and high-affinity nucleic acid recognition

5. LNA (Locked Nucleic Acids): Synthesis of the adenine, cytosine, guanine, 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation, and unprecedented nucleic acid recognition

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