NOAEL cancer therapy: a tumor targetable docetaxel–inorganic polymer nanohybrid prevents drug-induced neutropenia

Author:

Jin Geun-Woo1,Choi Goeun234ORCID,Piao Huiyan2,Rejinold N. Sanoj2,Asahina Shunsuke5ORCID,Choi Soo-Jin6,Lee Hwa Jeong7,Choy Jin-Ho28910ORCID

Affiliation:

1. R&D Center, CnPharm Co., Ltd, Seoul 03759, Republic of Korea

2. Intelligent Nanohybrid Materials Laboratory (INML), Institute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan 31116, Republic of Korea

3. College of Science and Technology, Dankook University, Cheonan 31116, Republic of Korea

4. Department of Nanobiomedical Science and BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan 31116, Republic of Korea

5. JEOL Ltd. SM Business Unit, 3-1-2 Musashino, Akishima-shi, Tokyo 196-8558, Japan

6. Division of Applied Food System, Major of Food Science & Technology, Seoul Women's University, Seoul 01797, Republic of Korea

7. Graduate School of Pharmaceutical Sciences, Ewha Womans University, 52 Ewhayeodae-gil, Seodaemun-gu, Seoul, 03760, Republic of Korea

8. Division of Natural Sciences, The National Academy of Sciences, Seoul 06579, Republic of Korea

9. Department of Pre-medical Course, College of Medicine, Dankook University, Cheonan 31116, Republic of Korea

10. International Research Frontier Initiative (IRFI), Institute of Innovative Research, Tokyo Institute of Technology, Yokohama 226-8503, Japan

Abstract

PTX is expected to be able to replace existing chemotherapy as it is free from toxicity, the biggest drawback of existing chemotherapy.

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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