Asymmetric organocatalytic (3 + 2) annulation of propargylic alcohols with indolylnaphthalenols: synergistic construction of axial and central chirality-Reference-Cited by-同舟云学术

Asymmetric organocatalytic (3 + 2) annulation of propargylic alcohols with indolylnaphthalenols: synergistic construction of axial and central chirality

Published:2023 Issue:1 Volume:10 Page:30-34
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Xia Yan¹,Liu Meiwen²,Qian Chenxiao²,Li Pengfei²^ORCID,Dong Mingxin¹^ORCID,Li Wenjun¹^ORCID

Affiliation:

1. Department of Medicinal Chemistry, School of Pharmacy, Qingdao University, Qingdao, Shandong, 266021, China

2. Shenzhen Grubbs Institute and Department of Chemistry, Guangdong Provincial Key Laboratory of Catalysis, College of Science, Southern University of Science and Technology, Shenzhen, Guangdong, 518055, China

Abstract

Organocatalytic enantioselective construction of chiral spiro N,N-acetal carbon stereocenters and axially chiral 3-arylindoles has been achieved in one pot.

Funder

Taishan Scholar Foundation of Shandong Province

Science, Technology and Innovation Commission of Shenzhen Municipality

Guangdong Provincial Key Laboratory Of Catalysis

Natural Science Foundation of Shandong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QO/D2QO01625G

Reference50 articles.