Determination of N-retinylidene-N-retinylethanolamine (A2E) levels in central and peripheral areas of human retinal pigment epithelium-Reference-Cited by-同舟云学术

Determination of N-retinylidene-N-retinylethanolamine (A2E) levels in central and peripheral areas of human retinal pigment epithelium

Published:2015 Issue:11 Volume:14 Page:1983-1990
ISSN:1474-905X
Container-title:Photochemical & Photobiological Sciences
language:en
Short-container-title:Photochem. Photobiol. Sci.

Author:

Adler Leopold¹²³⁴,Boyer Nicholas P.¹²³⁴,Anderson David M.⁵⁶⁷⁴,Spraggins Jeffrey M.⁵⁶⁷⁴,Schey Kevin L.⁵⁶⁷⁴,Hanneken Anne⁸⁹¹⁰⁴,Ablonczy Zsolt¹²³⁴,Crouch Rosalie K.¹²³⁴,Koutalos Yiannis¹²³⁴

Affiliation:

1. Department of Ophthalmology

2. Medical University of South Carolina

3. Charleston

4. USA

5. Mass Spectrometry Research Center

6. Vanderbilt School of Medicine

7. Nashville

8. Department of Molecular and Experimental Medicine

9. The Scripps Research Institute

10. La Jolla

Abstract

The levels of the bis-retinoid A2E cannot account for the high levels of lipofuscin fluorescence found in the central area of the human retinal pigment epithelium.

Funder

National Institutes of Health

Research to Prevent Blindness

Publisher

Springer Science and Business Media LLC

Subject

Physical and Theoretical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/PP/C5PP00156K

Reference41 articles.

1. The bisretinoids of retinal pigment epithelium

2. Phospholipid meets all-trans-retinal: the making of RPE bisretinoids

3. Retinal age pigments generated by self-assembling lysosomotropic detergents

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