Determination of N-retinylidene-N-retinylethanolamine (A2E) levels in central and peripheral areas of human retinal pigment epithelium

Author:

Adler Leopold1234,Boyer Nicholas P.1234,Anderson David M.5674,Spraggins Jeffrey M.5674,Schey Kevin L.5674,Hanneken Anne89104,Ablonczy Zsolt1234,Crouch Rosalie K.1234,Koutalos Yiannis1234

Affiliation:

1. Department of Ophthalmology

2. Medical University of South Carolina

3. Charleston

4. USA

5. Mass Spectrometry Research Center

6. Vanderbilt School of Medicine

7. Nashville

8. Department of Molecular and Experimental Medicine

9. The Scripps Research Institute

10. La Jolla

Abstract

The levels of the bis-retinoid A2E cannot account for the high levels of lipofuscin fluorescence found in the central area of the human retinal pigment epithelium.

Funder

National Institutes of Health

Research to Prevent Blindness

Publisher

Springer Science and Business Media LLC

Subject

Physical and Theoretical Chemistry

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