An arsenic trioxide nanoparticle prodrug (ATONP) potentiates a therapeutic effect on an aggressive hepatocellular carcinoma model via enhancement of intratumoral arsenic accumulation and disturbance of the tumor microenvironment-Reference-Cited by-同舟云学术

An arsenic trioxide nanoparticle prodrug (ATONP) potentiates a therapeutic effect on an aggressive hepatocellular carcinoma model via enhancement of intratumoral arsenic accumulation and disturbance of the tumor microenvironment

Published:2019 Issue:19 Volume:7 Page:3088-3099
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Fu Xin¹²³⁴,Liang Qing-rong⁵³⁴,Luo Rong-guang⁶⁷⁸⁴,Li Yan-shu⁹⁴,Xiao Xiao-ping⁵³⁴,Yu Lu-lu⁵³⁴,Shan Wen-zhe⁵³⁴,Fan Guang-qin¹²³⁴,Tang Qun¹²³⁴⁵^ORCID

Affiliation:

1. Jiangxi Provincial Key Laboratory of Preventive Medicine

2. School of Public Health

3. Nanchang University

4. P. R. China

5. Institute for Advanced Study

6. Department of Medical Imaging and Interventional Radiology

7. the First Affiliated Hospital of Nanchang University

8. Nanchang 330006

9. Jiangxi Supervision and Inspection Center for Medical Devices

Abstract

An arsenic trioxide nanoparticle prodrug has a therapeutic effect on a transgenic liver cancer model by disturbing the tumor micro-environment and increasing the delivery efficiency.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2019/TB/C9TB00349E

Reference62 articles.

1. Hepatocellular Carcinoma

2. Hepatocellular carcinoma

3. Drug development: Try and try again