Efficacious and sustained release of an anticancer drug mitoxantrone from new covalent organic frameworks using protein corona

Author:

Bhunia Subhajit12ORCID,Saha Pranay2ORCID,Moitra Parikshit23ORCID,Addicoat Matthew A.4ORCID,Bhattacharya Santanu52ORCID

Affiliation:

1. Department of Chemistry & Biochemistry, University of Texas at El Paso, El Paso, Texas 79968, USA

2. School of Applied and Interdisciplinary Sciences, Indian Association for the Cultivation of Science, Kolkata, West Bengal 700032, India

3. Department of Pediatrics, Center for Blood Oxygen Transport and Hemostasis, University of Maryland Baltimore School of Medicine, Health Sciences Facility III, Baltimore, Maryland 21201, USA

4. School of Science and Technology, Nottingham Trent University, Nottingham, NG11 8NS, UK

5. Department of Organic Chemistry, Indian Institute of Science, Bangalore, 560012, India

Abstract

Solid porous and crystalline covalent organic frameworks (COFs) are characterized by their higher specific BET surface areas and functional pore walls, which allow the adsorption of various bioactive molecules inside the porous lattices.

Funder

Department of Science and Technology, Ministry of Science and Technology, India

Council of Scientific and Industrial Research, India

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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