Towards non-invasive monitoring of non-melanoma skin cancer using spatially offset Raman spectroscopy

Author:

Vardaki Martha Z.12ORCID,Pavlou Eleftherios1,Simantiris Nikolaos3,Lampri Evangeli4,Seretis Konstantinos5ORCID,Kourkoumelis Nikolaos1ORCID

Affiliation:

1. Department of Medical Physics, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece

2. Institute of Chemical Biology, National Hellenic Research Foundation, 48 Vassileos Constantinou Avenue, Athens, 11635, Greece

3. Ionian University, Department of Informatics, Corfu, 49132, Greece

4. Department of Pathology, Faculty of Medicine, University of Ioannina, 45110 Ioannina, Greece

5. Department of Plastic Surgery, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece

Abstract

Spatially offset Raman spectroscopy revealed a correlation of protein and lipid content with non-melanoma skin cancer. Multiple factor analysis on the same data demonstrated clustering based on pathology rather than interpatient variability.

Funder

European Social Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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