Targeting extracellular lectins of Pseudomonas aeruginosa with glycomimetic liposomes-Reference-Cited by-同舟云学术

Targeting extracellular lectins of Pseudomonas aeruginosa with glycomimetic liposomes

Published:2022 Issue:4 Volume:10 Page:537-548
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Metelkina Olga¹²³,Huck Benedikt⁴⁵,O'Connor Jonathan S.⁶⁷,Koch Marcus⁸,Manz Andreas⁶⁷^ORCID,Lehr Claus-Michael⁴⁵,Titz Alexander¹²³^ORCID

Affiliation:

1. Chemical Biology of Carbohydrates, Helmholtz Institute for Pharmaceutical Research Saarland, Helmholtz Centre for Infection Research, 66123 Saarbrücken, Germany

2. Deutsches Zentrum für Infektionsforschung (DZIF), Standort Hannover-Braunschweig, 38124 Braunschweig, Germany

3. Department of Chemistry, Saarland University, 66123 Saarbrücken, Germany

4. Drug Delivery, Helmholtz Institute for Pharmaceutical Research Saarland, Helmholtz Centre for Infection Research, 66123 Saarbrücken, Germany

5. Department of Pharmacy, Saarland University, 66123 Saarbrücken, Germany

6. KIST Europe, 66123 Saarbrücken, Germany

7. Department of Systems Engineering, Saarland University, 66123 Saarbrücken, Germany

8. INM – Leibniz Institute for New Materials, 66123 Saarbrücken, Germany

Abstract

Glyco-functionalized liposomes inhibiting two Pseudomonas aeruginosa lectins LecA and LecB using multivalent interactions. The impact of the ligand density of the surface was studied by the specially designed in vitro microfluidic model.

Funder

European Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2022/TB/D1TB02086B

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