Ultrasensitive glucose detection from tears and saliva through integrating a glucose oxidase-coupled DNAzyme and CRISPR

Ultrasensitive glucose detection from tears and saliva through integrating a glucose oxidase-coupled DNAzyme and CRISPR–Cas12a

Author:

Zhang Caiying¹,Yao Hongfeng²,Ma Qiang¹,Yu Bin³^ORCID

Affiliation:

1. Department of Endocrinology, Zhuji Affiliated Hospital of Shaoxing University, Zhuji City, Zhejiang Province, 311800, China

2. Department of Clinical Laboratory, Zhuji Affiliated Hospital of Shaoxing University, Zhuji City, Zhejiang Province, 311800, China

3. Department of medical administration, the Second Affiliated Hospital of Zhejiang University, Hangzhou City, Zhejiang Province, 312000, China

Abstract

The accurate and sensitive detection of glucose from secretory clinical samples, such as tears and saliva, remains a great challenge.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

Reference23 articles.

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