Halo-perfluoroalkoxylation of <i>gem</i>-difluoroalkenes with short-lived alkali metal perfluoroalkoxides in triglyme-Reference-Cited by-同舟云学术

Halo-perfluoroalkoxylation of gem-difluoroalkenes with short-lived alkali metal perfluoroalkoxides in triglyme

Published:2024 Issue:25 Volume:15 Page:9574-9581
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Kawai Koki¹,Kato Yoshimitsu²,Araki Taichi²,Ikawa Sota²,Usui Mai²,Hoshiya Naoyuki³,Kishikawa Yosuke³,Escorihuela Jorge⁴^ORCID,Shibata Norio¹²^ORCID

Affiliation:

1. Department of Nanopharmaceutical Sciences, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya 466-8555, Japan

2. Department of Life Science and Applied Chemistry, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya 466-8555, Japan

3. Technology Innovation Center, DAIKIN Industries, Ltd, 1-1 Nishi-Hitotsuya, Settsu, Osaka 566-8585, Japan

4. Departamento de Química Orgánica, Universitat de València, Avda. Vicente Andrés Estellés S/N, Burjassot 46100, Valencia, Spain

Abstract

The synthesis of long-chain perfluoroalkyl ethers remains a challenge. The stabilization of longer-chain perfluoroalkoxides with triglyme-encapsulated potassium ions enabled the synthesis of bis(α,α-difluoro)ethers with gem-difluoroalkenes.

Funder

Core Research for Evolutional Science and Technology

Japan Science and Technology Agency

Kyoto Institute of Technology

Universitat de València

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/SC/D4SC02084G

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1. α-Fluorinated Ethers, Thioethers, and Amines: Anomerically Biased Species

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