Characterisation of protein aggregation with the Smoluchowski coagulation approach for use in biopharmaceuticals-Reference-Cited by-同舟云学术

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Characterisation of protein aggregation with the Smoluchowski coagulation approach for use in biopharmaceuticals

Published:2018 Issue:29 Volume:14 Page:6001-6012
ISSN:1744-683X
Container-title:Soft Matter
language:en
Short-container-title:Soft Matter

Author:

Zidar Mitja¹²³⁴⁵,Kuzman Drago⁵⁶⁷⁸⁹,Ravnik Miha¹²³⁴¹⁰^ORCID

Affiliation:

1. Faculty of Mathematics and Physics

2. University of Ljubljana

3. 1000 Ljubljana

4. Slovenia

5. Protein Biophysics and Bioinformatics

6. Technical Development Biologics Mengeš

7. Lek Pharmaceuticals d.d.

8. part of Novartis

9. 1234 Mengeš

10. Jozef Stefan Institute

Abstract

Aggregation mechanisms from nano-scale to visible particles are shown, as relevant for long-term storage of biopharmaceuticals.

Funder

Javna Agencija za Raziskovalno Dejavnost RS

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/SM/C8SM00919H

Reference40 articles.

1. Ron R. Kopito: Unfolding the Secrets of Protein Aggregation

2. Potent antibody therapeutics by design

3. Efficacy of B-Cell–Targeted Therapy with Rituximab in Patients with Rheumatoid Arthritis

4. Management of patients with inflammatory bowel disease: current and future treatments

5. Pertuzumab plus Trastuzumab plus Docetaxel for Metastatic Breast Cancer

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