The emerging landscape of microfluidic applications in DNA data storage

Author:

Luo Yuan12ORCID,Cao Zhen34,Liu Yifan56ORCID,Zhang Rong5,Yang Shijia12,Wang Ning12,Shi Qingyuan5,Li Jie5ORCID,Dong Shurong34,Fan Chunhai7ORCID,Zhao Jianlong128

Affiliation:

1. State Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai 200050, China

2. Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beijing 100049, China

3. College of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310027, China

4. International Joint Innovation Center, Zhejiang University, Haining 314400, China

5. School of Physical Science and Technology, ShanghaiTech University, Shanghai, 201210, China

6. Shanghai Clinical Research and Trial Center, Shanghai, 201210, China

7. School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules and National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai 200240, China

8. Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, 100101, P.R. China

Abstract

Microfluidics offers great potential as an enabling technological platform for the burgeoning field of DNA data storage, making critical contributions to improving the performance in data processing, as well as system integration and automation.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Chinese Academy of Sciences

Natural Science Foundation of Zhejiang Province

Fundamental Research Funds for the Central Universities

Science and Technology Commission of Shanghai Municipality

ShanghaiTech University

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Reference169 articles.

1. D.Reinsel , J.Gantz and J.Rydning , Data age 2025: the digitization of the world from edge to core , International Data Corporation , 2018 , https://www.seagate.com/files/www-content/our-story/trends/files/idc-seagate-dataage-whitepaper.pdf , (accessed September 2022)

2. Molecular digital data storage using DNA

3. Encoding information into polymers

4. Coming of age: ten years of next-generation sequencing technologies

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