Diastereoselective synthesis of atropisomeric pyrazolyl pyrrolo[3,4-d]isoxazolidines via pyrazolyl nitrone cycloaddition to facially divergent maleimides: intensive NMR and DFT studies
Author:
Affiliation:
1. Chemistry Department
2. Faculty of Science
3. Assiut University
4. Assiut
5. Egypt 71516
Abstract
Diastereoselective pyrazole-based atropisomeric cycloadducts were formed by cycloaddition of a pyrazole-based nitrone and maleimides with restricted rotation around C–N bond caused by bulk ortho substitution.
Funder
Assiut University
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/RA/C9RA10039C
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