Light-activated quantum dot potentiation of antibiotics to treat drug-resistant bacterial biofilms

Author:

Stamo Dana F.1234,Nagpal Prashant53463,Chatterjee Anushree12346ORCID

Affiliation:

1. Chemical and Biological Engineering

2. University of Colorado Boulder

3. Boulder

4. USA

5. Antimicrobial Regeneration Consortium

6. Sachi Bioworks, Inc.

Abstract

CdTe-2.4 eV quantum dots (QDs) show excellent efficacy due to their tunability and photo-potentiation for sterilizing drug-resistant planktonic cultures without harming mammalian cells but this QD fabrication has not been tested against biofilms.

Funder

National Science Foundation

National Aeronautics and Space Administration

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

Reference38 articles.

1. Antibiotic Resistance Threats in the United States, 2019 , 2019 , p. 148

2. World Health Organization , 2019 Antibacterial Agents in Clinical Development: An Analysis of the Antibacterial Clinical Development Pipeline , 2019

3. Antibiotic discovery goes underground

4. Transcriptome-based design of antisense inhibitors potentiates carbapenem efficacy in CREEscherichia coli

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