A modular approach to the bisbenzylisoquinoline alkaloids tetrandrine and isotetrandrine-Reference-Cited by-同舟云学术

A modular approach to the bisbenzylisoquinoline alkaloids tetrandrine and isotetrandrine

Published:2020 Issue:16 Volume:18 Page:3047-3068
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Schütz Ramona¹²³⁴^ORCID,Meixner Maximilian⁵⁶⁷⁴,Antes Iris⁵⁶⁷⁴,Bracher Franz¹²³⁴^ORCID

Affiliation:

1. Department of Pharmacy – Center for Drug Research

2. Ludwig-Maximilians University Munich

3. 81377 Munich

4. Germany

5. TUM School of Life Sciences

6. Technical University Munich

7. 85354 Freising

Abstract

A modular short-step synthesis of the bisbenzylisoquinoline alkaloids tetrandrine and isotetrandrine was developed employingN-acyl-Pictet–Spengler reaction and Ullman diaryl ether synthesis as central steps.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB00078G

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